Diabetes is a disease that feeds on the patient’s ignorance. Throughout time, it gives little signs here and there, until it slowly and painlessly, leads the patients on an abrupt path towards invalidity and, eventually, death.

Diabetes itself is dangerous only because of the consequences of high blood sugar levels. Insulin or pills can control these. Nevertheless, the consequences of diabetes on the long term are the ones to be carefully considered! When the high level of blood glucose is high over longer periods of time, the nerves and the blood vessels are slowly degrading until the patient starts suffering of polyneuropathies (among which, the degrading of the optic nerve is the most frequent cause of sight loss, even leading to blindness, in the case of 85% of the patients), arteriopathies, kidney failure and ulcerations of the calves that do not usually respond to the usual treatment, sometimes leading to amputation. The blood vessels that are affected most often are the ones found in the heart, brain and kidney area. Since patients suffering from diabetes have a very low tolerance at infections, “complications of other complications” may appear, mostly with skin infections or the ones of the respiratory or the urinary system.
The success of ozone therapy in the fight with diabetes is given mostly by the fact that it aims at its main cause (hyperglycemia), but at the same time at its side effects. When facing difficult complications, conventional medicine comes up with treatment schemes that do not always pay off and that is mostly because the very mechanism through which they are supposed to work has already been compromised by the disease. That is why one very beneficial “side effect” of ozone therapy is that, while healing the damaged tissues, it also protects and strengthens the healthy ones, thus helping the body respond well to the conventional therapies. While some patients have complications very early on and others never get to this stage, most patients are exposed to this risk on the long run, displaying severe consequences throughout a period of 15-20 years after the debut of the disease.


The main method of ozone treatment is major autohemotransfusion: 70 to 120 ml of blood is collected in a sterile and voided recipient and then it is mixed with the same quantity of ozone. The ratio is decided by the doctor. The mixture is then reinjected through an IV for a period of 20-30 minutes

Major autohemotherapy
Major autohemotherapy increases the aerophilous glycolysis in the cells, thus leading to a lowering of the blood sugar levels and, in time, leads to a lowering in insulin intake or oral medication required. Ozone also improves local oxygenation through several mechanisms. Directly, by splitting a molecule into an ozone molecule and a free radical (that is combined with another radical generating another molecule), but also indirectly, by the action that it has on erythrocytes, by the increase of 2,3 diphosphoglycerate, increasing the degree of release of oxygene in tissues from oxyhemoglobine. Since one major problem for the patients suffering from diabetes is precisely the fact that oxygene is no longer released from the erythrocytes in the tissues, therefore causing major hypoxia in time, ozone therapy acts exactly on the main cause of every complication. The increase in the tissue oxygenation leads to the formation of new blood vessels that flow through the areas affected by arteriopathy. Having the qualities of a platelet antiaggregant, ozone contributes to the decrease of cardiovascular risks. The decrease of cholesterol and triglycerides levels throughout the therapy produces, in fact, a decrease of risk factors and prolongues the duration of life.
Diabetic leg
Nevertheless, the most spectacular effects of ozone therapy are in the case of diabetes patients that come to the doctor’s office with impressive ulcerations in the calf area. Very often close to having both legs amputated, they come to the ozone therapy clinic after having tried all treatments possible or after surgeons told them that amputation is their last resort. In these cases, besides autohemotherapy, applying ozone locally is of help. Practically, the wound is cleaned of dead tissue, until only the healthy tissue remains. The leg is then washed with ozoned water and is introduced in a special bag. Highly concentrated ozone is then infused in the bag in order to obtain an antibacterial and antifungal effect, based on its oxidative properties. In autohemotransfusions, since we aim at a different type of effect, we will use a lower concentration on this type of patients. The ozone treatment is individualized according to the stage of each patient’s disease and to their respective level of tolerance. If locally applied ozone in bags is meant to do a hygiene of the ulceration and thus healing it from the outside, the ozone introduced through autohemotransfusion takes its effects from the inside of the body. It will lead to the formation of new blood vessels, the improvement of oxygenation and consequently to tissue regeneration. The first results can be seen only after 5-6 sessions
The duration of the therapy
The duration of the therapy is established according to the individual response of every patient to the treatment.